>>> US After Hours Summary: STNE +21.3%, OKTA +16.5%, LULU +1.7%, RH +1.2% highe

After Hours Summary: STNE +21.3%, OKTA +16.5%, LULU +1.7%, RH +1.2% higher on earnings; JOAN -15.4%, ZUMZ -8.6%, CRWD -2.5% lower on earnings

After Hours Gainers:

Companies trading higher in after hours in reaction to earnings/guidance: STNE +21.3%, OKTA +16.5%, NX +9.5%, PD +3.4%, PHR +2.7%, NAPA +2%, LULU +1.7%, RH +1.2% (also authorizes an additional $2 bln to stock repurchase program), ALK +1.2% (updates its Q2 outlook; raises Q2 revenue guidance)

Companies trading higher in after hours in reaction to news: LOCO +10.8% (names new CFO), CHGG +8.1% (increases securities repurchase program by $1 bln), CLPT +1.8% (receives certification for the Medical Device Single Audit Program), WOR +0.8% (acquires Level5 Tools for $55 mln), COST +0.2% (May adjusted comps grow +11.8%), PINS +0.2% (to acquire THE YES), COIN +0.1% (will extend its hiring pause for the foreseeable future and rescind a number of accepted offers)

After Hours Losers:

Companies trading lower in after hours in reaction to earnings/guidance: JOAN -15.4%, ZUMZ -8.6%, HCP -8%, ASAN -4.9%, COO -2.8%, CRWD -2.5%, IOT -1.7%

Companies trading lower in after hours in reaction to news: KSS -7.7% (auction delayed indefinitely as several suitors bowed out, according to NY Post), KREF -4.1% (stock offering), MMAT -1.6% (stock offering), NOC -1% (awarded Missile Defense Agency contract with ceiling value of $249 mln), GPN -0.5% (names new CFO), DM -0.5% (stock offering)

FT : Fire Island — Disney’s gay romcom comes loaded with controversy

Fire Island — Disney’s gay romcom comes loaded with controversy
Asian-American-led movie mixing Jane Austen with ketamine and fellatio arrives in tricky times for the studio

In chipper new comedy Fire Island, the New York resort of the same name is called the “gay Disney World”. Last summer when the movie was shot, the line would have merely seemed impish, given that the financing came from Disney itself. Now it can’t help but sound loaded in a gay romance released in tricky times for the company’s relationship with the LGBT+ community.

First came a lack of response from the company in March to Florida’s new “Don’t Say Gay” school legislation, prompting angry staff walkouts at Disney. Then came a change of course into public opposition of the bill that angered Republicans, leading to Disney World being stripped of its ability to “self-govern” in the state. All things considered, Fire Island could be taken as a sincere landmark movie for the studio, Disney merely exploiting a market — or both. Either way, it finds itself still more caught up in the American culture war than it would have been in 2021.

Kudos to the film, then, that it feels as breezy as it does, a wry, intelligent riff on Pride and Prejudice. Jane Austen is a favourite of the resolutely single Noah (Joel Kim Booster, who also wrote the script) for all he disputes her universal truth that every single man “must be in want of a wife”. Here in place of the Bennet sisters, Noah and his affable misfit group of friends arrive on the island for their annual fix of hedonism, despite being poor relations amid doctors and lawyers with zero body fat.

Booster deals deftly not just with sexuality but with class and race (he and co-star Bowen Yang are Asian American), a smart grasp of pop culture adding another flavour to the familiar tale of lovestruck crossed wires. Ketamine and fellatio are new ground both for Austen adaptations and Disney, but the movie’s most radical step might be how subtly conventional it really is. Progress means sugar-coated romcoms for all.

>>> US Early premarket gappers


Early premarket gappers

  • Gapping up:
    • CHWY +17.2%, RPTX +17%, PSTG +12.5%, APRN +11.1%, PATH +11.1%, KIND +9.3%, MDB +9.2%, CRDO +8.5%, ESTC +7.4%, SANA +5.6%, VEEV +4.3%, PVH +4.1%, NTAP +3.4%, RIOT +2.8%, CMTL +2.7%, GSM +2.5%, ASGN +2.3%, BYD +2.1%, DHX +1.4%, VAL +1.4%, ORCL +1%, DAL +0.9%, BA +0.9%, SAIL +0.9%, DSGX +0.9%
  • Gapping down:
    • AI -23.6%, OZON -19%, HPE -6.2%, CNCE -5.4%, DAWN -4.9%, MGY -4.5%, OWL -4%, RDUS -2.3%, IGT -1.7%, FUN -1.6%, ARCB -1.3%, ANIP -1%

>>> What to look at today : 2nd of June 2022

Stocks in Asia fell Thursday as central bankers amplified hawkish messages in their quest to rein in inflation, weighing on risk assets. Oil sank.vvvvAn MSCI Inc. gauge of Asia-Pacific shares retreated for a second day, with equities in Hong Kong leading declines amid tough virus curbs. US contracts fluctuated after stocks dropped on Wall Street. US manufacturing activity and job openings data fueled concern the Federal Reserve will need to get more restrictive to slow runaway price gains. Treasuries held losses, with 10-year yields edging up above 2.90%. Traders raised bets on the path for rate hikes and the Fed started its balance-sheet reduction process. The dollar was steady while the yen held near 130 per dollar after its recent decline on the prospect of widening interest rate differentials with the US. Crude oil slid on a report that Saudi Arabia is ready to pump more oil if Russian output declines. OPEC+ is scheduled to meet to discuss supply policy.  The Bank of Canada raised its overnight rate by a half percentage point, as expected, and warned that it may act “more forcefully” if needed to tackle inflation.  Chinese stocks fluctuated. Beijing ordered state-owned policy banks to set up an 800 billion yuan ($120 billion) line of credit for infrastructure projects as it leans on construction to stimulate an economy battered by coronavirus lockdowns.

Nikkei -0,10% Hang Seng -1,57% CSI _0,06% Shanghai +0,11% Shenzen +0,38%

Eur$ 1,0659 CNH 6,7507 CNY 6,9888 JPY 130,08 GBP CHF 0,9632 RUB 64,4375 TRY 16,4330 WTI$ 113,07 Gold 1,844,60 XBT 29769 ETH 1,810, 65

S&P +0,10% Nasdaq +0,11% EuroStoxx +0,2&% FTSE Closed Dax +0,13% SMI

Macro :
- Oil Slides on Report Saudi Prepared to Boost Output, Biden Visit
- JPMorgan’s Kolanovic Sees Sunny Stocks as Dimon Braces for Storm
- Bitcoin Retreats to Consolidate Below $30,000; Solana Tumbles
- Chinese Builder Gets ‘Game-Changer’ Moment on State Support
- US Cancels $5.8B in Student Loans Linked to Corinthian Colleges
- Royal Mail, ITV to Exit FTSE 100; Centrica, Unite Promoted: LSE
- Brazil to Raise $500 Million to Pay Creditors of Fallen Businessman Eike Batista
- Denmark Investigates Possible Russian Sanctions Breaches: Borsen

Keep an eye on :
- ASOS LN : Royal Mail, ITV to Exit FTSE 100; Centrica, Unite Promoted: LSE
- BALDB SS : Balder’s Head of Finance Resigns After Insider Trading Sentence
- SAB SM : David Booth’s Dimensional Fund Buys 3% Stake in Banco Sabadell
- DIE BB : Belgian May Car Registrations Drop 16.7%; D’Ieteren Has 23.3%
- DWS GY : DWS Chief’s Days Were Already Numbered When the Police Showed Up
- ELIS FP : Elis Signs a New 10-Year USPP Financing for $175M
- IPN FP : Ipsen CEO Eyes Acquisitions to Bolster Pipeline: Le Figaro
- BAER SW : Julius Baer Sells Fransad Gestion in Management Buyout; No Terms
- FB US : Sheryl Sandberg Steps Down as Meta Platforms COO: TMT Wrap
- NEXI IM : BT Sport JV Probed, Nexi Buys BPER Payment Unit: EMEA Tech Wrap
- NOVN SW : Novartis in Pact With ASH to Fight Sickle Cell Disease in Africa
_ OERL SW : Oerlikon Enters Pact to Sell Ops in Russia
- PSH NA : Pershing Square Holdings May Net Performance -9.5%
- RNO FP : Renault, Managem Sign Pact for Cobalt Supply
- RCO FP : Remy Cointreau FY Current Operating Income Beats Estimates
- SEZI SS : Senzime Offering of 5.26m Shares Prices at SEK19/Share
- SR1V FH : Finnish SRV Group in Talks to Sell Russian Assets: Vedomosti
- SRG IM : Belgium’s TES Hires Former Snam CEO to Lead Hydrogen Push
- SQN SW : Swissquote Being Probed by Swiss Regulator For Rule Violations
- TUNG LN : Pagero Says Terms of Offer for Tungsten Will Not Be Increased
- VOW GY : Portugal Light Vehicle Sales Fell 25% in May, Acap Says
- ZEAL DC : Zealand Pharma Offers 2.89m Shares at DKK95/Share

5ZH) Researchers Closer To Creating Blood Test For Suicide Risk

Researchers Closer To Creating Blood Test For Suicide Risk
BY TYLER DURDEN
THURSDAY, JUN 02, 2022 - 04:45 AM
Researchers have discovered an approach to identify blood biomarkers that could predict the risk of suicide in patients with depression, bringing them one step closer to developing a potential blood test for use on future patients thanks to a study by researchers at the University of California–Irvine (UCI) and Pritzker Research Consortium.
A student crosses the University of California–Irvine campus in Irvine, Calif., on Sept. 25, 2020. (John Fredricks/The Epoch Times)
Suicides have increased to nearly 50,000 deaths yearly in the United States and around 800,000 total globally, according to the team’s research now published in Translational Psychiatry, a peer-reviewed medical journal launched in 2011. The 2022 study further shows clinical depression as the most common diagnosis among suicides.
Even more troubling is that in the United States alone, suicide rates have increased by more than 35 percent over the last 20 years, the study says, making it the tenth leading cause of death.
“Identifying those at the highest risk is a pressing challenge,” researchers note in the literature, adding that “suicide prevention strategies and current medications, although helpful, have not stemmed the increase in self-inflicted deaths.”
As such, researchers launched an investigation to see if a blood biomarker signature for depression could be identified in post-mortem patients who took their own lives, studying both brain and blood cells. Their efforts were successful.
In their research, scientists found that non-preserved blood can be used to discover a gene that, when expressed or activated, makes people at a higher risk of suicide.
Not only can this discovery help providers pinpoint suicidal individuals, the results can also help researchers understand molecular changes in suicide victims, which may be of great use in treating the illness moving forward.
“That is so cool, I didn’t even know you could test for something like that … in someone’s blood,” a source diagnosed with depression, who wished to remain anonymous, told The Epoch Times.
“I wish that test was already available when I was in high school.”
The study uses a novel gene expression approach—a way to look for clusters of genes encoded in our DNA that make people at higher risk for certain conditions—in this case the genetic code specific to putting people at risk of suicidal tendencies.
Research further shows that many individuals do not disclose suicidal intentions despite frequent contact with health care professionals and that an estimated 30 percent of suicides visit a healthcare provider within a month of taking their lives.
As such, once developed this blood test can be administered during such medical visits, potentially helping to identify high-risk individuals before it’s too late.
“These blood biomarkers are an important step toward developing blood tests to identify patients with imminent risk of ending their lives,” said corresponding author Dr. Adolfo Sequeira, associate researcher in the Department of Psychiatry & Human Behavior at the UCI School of Medicine in a statement.