FT : Omicron sub-variant BA.2.75 spreads across India and parts of Europe

Omicron sub-variant BA.2.75 spreads across India and parts of Europe
The strain has been detected in Germany, the Netherlands, Japan, the UK and the US

An Omicron sub-variant that is spreading rapidly in India and has been detected in several European countries may be better than other coronavirus strains at overcoming immunity provided by prior infection and vaccines.

BA.2.75, which has been nicknamed Centaurus, appeared to have mutated in a way that could indicate “major immune escape”, said the World Health Organization’s chief scientist Soumya Swaminathan, adding that it showed a “clear growth advantage” over other variants in India. Global health authorities issued a similar warning when the highly mutated Omicron variant emerged late last year.

The strain has been detected in a number of countries including Germany, Japan, the UK and the US. Dutch health authorities on Wednesday became the latest to announce they had detected the strain.

“We now have 169 sequences from 12 countries — the increase observed is despite the reduction of [samples] in [genomic sequencing platform] Gisaid,” said Swaminathan.

She stressed that it still was not known whether the variant was more severe, more transmissible and immune evasive, or only the latter. “Every future variant will have these advantages if it has to out compete previous strains,” she said. A growth advantage could be due to intrinsic qualities of the virus or to changes in population immunity.

The variant was first identified in India and the nickname Centaurus later circulated on Twitter. Global health authorities were not involved in providing a name. The WHO, which oversees the process, named Omicron and would not provide another for a sub-variant.

The strain’s advance comes as health authorities contend with a resurgence of the pandemic, largely fuelled by the BA.5 Omicron sub-variant. The WHO said it had seen an “increase in trend” in case reports over the past week, something that was “concerning” given the reduction in global coronavirus testing.

European health authorities this week recommended wider eligibility for second boosters, saying those over 60 and those who are immunocompromised should get one. US authorities had previously issued a similar call.

“Prudent governments are really looking at their plans,” said Mike Ryan, the WHO’s executive director for health emergencies, referring to authorities’ preparations for an expected surge in infections later this year.

Governments have also taken the unusual step of opening up second boosters to broader parts of their populations before Omicron-variant vaccines become available later this year.

The deployment of Omicron-variant shots has been backed by EU and US regulators as well as the WHO, as it appears likely that coronavirus will continue to evolve.

Peter English, a retired consultant in public health, said the spread of the variant called for caution.

“The virus is still transmitting, very widely. In doing so it is mutating. Some variants are fitter than previous variants — intrinsically more transmissible and/or better able to evade immune responses,” he said. “Immunity lasts less time than we had hoped, so people can be infected repeatedly, with cumulative damage.”

Current vaccines are modelled on the strain of coronavirus as it first emerged in Wuhan, China, more than two years ago. They continue to retain high levels of protection against severe disease, but their efficacy is waning as more time lapses from the first rounds of vaccinations and the virus continues to evolve.

The WHO’s Ryan compared the protection afforded by vaccines against Covid to a wall protecting a castle. “It gets weak, it gets cracks, there are holes in the wall,” he said, adding that immunological memory “fades over time”.

FT : Alan Howard’s adventures in cryptoland

Alan Howard’s adventures in cryptoland
Media-shy hedge fund billionaire has quietly been building a digital assets empire

Cryptocurrency-based trivia games, horseracing non-fungible tokens and privacy specialists are all part of a large and growing digital assets empire that media-shy hedge fund billionaire Alan Howard has quietly been building, according to analysis by the Financial Times.

Howard is an influential figure in the hedge fund industry thanks to the success of Brevan Howard Asset Management, the $23bn macro trading firm he co-founded. In recent years though, he has been slowly relinquishing some of his roles at the firm to become a major force in crypto venture capital in both Europe and the US.

The FT has compiled a list of 43 investments by Howard in crypto companies and projects — ranging from well-known businesses like exchange FTX, to a start-up incubator and smaller NFT projects — based on information from venture capital databases Crunchbase, PitchBook and Dealroom and public announcements.

Howard has made his investments over the past five years, sometimes alongside big private equity groups such as Tiger Global, SoftBank and Peter Thiel.

“It looks incredibly random until you put it on a map and then it looks incredibly strategic,” said a crypto company executive who had worked with Howard. “He wants to be involved in all facets of the industry.” 

Howard’s interest in cryptocurrencies began in 2017, according to people who have worked with him, and he has continued to invest in the sector despite the wild ups and downs in the market.

“He has a 10- to 15-year vision. While everyone was running out, he was running in,” the executive said of Howard’s decision to keep investing in companies during the 2018 crypto bust. The pace of these investments accelerated in the past two years, and has continued despite the brutal sell-off in recent months.

Howard, who declined to be interviewed for this article, has maintained a lower profile than other major crypto investors such as Galaxy Digital’s Mike Novogratz. However, he has invested alongside Galaxy on projects including the exchange Bullish Global and Derby Stars, which describes itself as “a horseracing metaverse game where players can breed, grow, build and trade”.


Industry executives say the breadth of Howard’s investment portfolio puts him alongside Galaxy and the Connecticut-based crypto conglomerate Digital Currency Group as a major force in the sector.

“They have very big ambitions in crypto,” said a crypto investor who has worked directly with Howard.

Howard has rarely spoken publicly about his hedge fund or crypto investments, although he did comment in an email interview published by crypto news website The Block in May.

Howard said crypto is “an important macro trend” but that because digital assets are still rather a new asset class “it’s most prudent to invest across the entire crypto ecosystem in a highly diversified manner”.

Hedge funds have become increasingly interested in crypto investment in recent years, the huge growth and returns attracting the attention of an industry that has sometimes struggled to make money over the past decade. Many hedge funds have also started trading crypto for this reason.

“Whilst we see a number of macro investment managers launching or considering the launch of a crypto fund . . . Alan Howard has invested more broadly, publicly and directly into the digital asset ecosystem, including middle and back office services and digital asset platforms,” said Quentin Thom, co-head at perfORM Due Diligence Services.

Howard, who got married last month in a lavish event on the shores of Lake Como, began stepping back from some of his hedge fund roles in 2019, when he handed over the position of chief executive of Brevan Howard to chief risk officer Aron Landy, although he continues to control the firm, according to regulatory filings.

This happened as Brevan Howard was making a strong recovery from a long run of poor performance when the firm’s master fund, which had previously never suffered a down year, lost money in three out of four calendar years between 2014 and 2017 and the firm’s assets plunged from $40bn to as low as $6bn.

Last year, Howard redeemed external investors in the AH fund he personally managed and which had made huge gains from the Italian bond shock in 2018. While he continues to have a trading book as part of the master fund, he rarely trades, said people familiar with the firm.

He is, however, still actively involved in Brevan Howard’s $1bn Digital Assets fund. “Alan is so focused on digital assets,” said one hedge fund investor.

A person familiar with Howard’s view said he is “heavily involved . . . in a variety of initiatives across Brevan Howard, including co-investing, strategy allocations and the crypto business through BH Digital”.

Howard told The Block in May that “BH Digital reflects my belief in the importance of investing across the entire ecosystem, regardless of instrument, in a diversified and well risk-managed way.”

His willingness to buy crypto assets directly contrasts with some other investors, who have preferred to buy equity stakes in companies operating in the crypto sector.

Howard has said that venture capital funding and investing directly in crypto tokens and currencies should be considered together because crypto projects often go public very early in their existence by selling tokens to investors.

With his venture capital investments, the list of deals also shows that in most crypto categories where Howard invests, he has tended to back more than one company and across the market.

For instance, he has invested in at least three exchanges and three custodians, companies that store digital assets for clients. He has also backed companies building crypto trading and portfolio management software, as well as several investment funds that are active in digital assets.

Other key parts of his crypto portfolio include Elwood, a trading software firm, start-up incubator WebN Group and Coremont Digital, the crypto- focused branch of the back-office company spun out of Brevan Howard. All three share a central London office with Brevan Howard.

Away from the companies that provide crypto market infrastructure, Howard has also made more niche investments. In November he invested in a fundraising by Iron Fish, a developer working on technology to enable completely private cryptocurrency transactions.

Howard is known for his long-term approach but his crypto portfolio has recorded a few exits. Newcastle-based crypto payments firm Bottlepay was sold to US crypto group NYDIG last year, while institutional trading platform Omniex was acquired by the Winklevoss twin’s Gemini group in January.

Howard’s personal stake in Elwood fell when the company raised $70mn in outside investment from backers including Goldman Sachs and Barclays at a roughly $500mn valuation. He did not take part in the round, but remains the majority owner.

He is also known as an art collector and is interested in “generative” digital art that has its roots in 1960s computer art. He promotes the sector through a monthly digital art salon in London.

Although the current market downturn has put off a lot of would-be crypto investors, it presents opportunities for patient, well-funded investors like Howard.

“In my opinion, he knows what he’s doing. He’s working with the brightest in the crypto industry and is very well advised,” said the investor who had worked with Howard.

“I wouldn’t be surprised to see him come out of the other side of this bear market as one of the biggest players alongside Galaxy. He’s positioning himself to take advantage of valuations.” 

FT : Celsius Network reveals $1.2bn shortfall in bankruptcy filing

Celsius Network reveals $1.2bn shortfall in bankruptcy filing
Crypto lender’s founder admits mistakes as digital asset group seeks court protection

Crypto lender Celsius Network has revealed a $1.2bn hole in its balance sheet caused by what chief executive Alex Mashinsky called “poor” investments and other “unanticipated” losses.

Celsius made the disclosure as it sought US bankruptcy protection this week after freezing customer funds in June, which made it the latest victim of the crash in crypto markets that has forced two other large companies into recent bankruptcy.

Mashinsky, who co-founded Celsius in 2017, laid bare the scale of the New Jersey-based company’s problems in a 61-page court filing on Thursday. It showed liabilities of $5.5bn, and assets of just $4.3bn.

The vast majority of the liabilities, $4.7bn, were attributed to Celsius users. The filing suggested they may face significant losses and blamed the company’s problems on a mixture of bad bets, market conditions and a failure to manage its rapid growth.

“The amount of digital assets on [Celsius’s] platform grew faster than the company was prepared to deploy. As a result, the company made what, in hindsight, proved to be certain poor asset deployment decisions,” Mashinsky wrote in the filing.

Celsius was one of a handful of crypto lenders that pulled in billions of dollars worth of assets from ordinary investors in recent years. It promised interest rates as high as 18 per cent on certain cryptocurrencies.

Canada’s second-largest pension fund, Caisse de dépôt et placement du Québec, and investment firm WestCap led a $600mn equity funding round last year that valued Celsius at $3bn.

The lender is the third big crypto company to file for bankruptcy, following crypto broker Voyager Digital and hedge fund Three Arrows Capital. All three have been hit by collapsing crypto asset prices and a freeze in credit in the market.

Mashinsky admitted a series of mistakes that had resulted in losses and detailed investments that had left Celsius unable to return money to customers as it suffered a bank run this year.

One was a $510mn loss discovered in 2021 when Celsius sought to recover collateral it had pledged to cover borrowings from an unnamed “private lending platform”. 

“The lender was unable to return the . . . collateral on a timely basis,” Mashinsky wrote. Some $440mn of that remains outstanding, he added.

Celsius also incurred losses of almost $100mn when collateral it had pledged to secure a loan from Tether — the stablecoin issuer that is an equity investor in Celsius — was liquidated by mutual agreement in recent months.

Mashinsky said about $1bn of Celsius’s funds were illiquid as they had been committed to the company’s bitcoin mining operation or invested in a version of the Ethereum network that has not been launched.

He suggested Celsius’s recovery plan could involve using bitcoin generated from its mining operations to “address its current cryptocurrency deficit”.

As well as admitting the company’s mistakes, he blamed “misinformation” in the media and on social media for encouraging customers to pull about $1bn worth of funds over five days in May.

Mashinsky said Celsius had been on its way to addressing its problems when the market turned this year.

“The company believes that it would have likely succeeded in the near future if the market had remained relatively stable.”

>>> US After Hours Summary: PINS +14.2% on WSJ report that activist Elliott Mgmt

After Hours Summary: PINS +14.2% on WSJ report that activist Elliott Mgmt has built large stake; CDXS -21.3% and TXG -12.8% fall on weak guidance; RRGB +2.5% gets a new CEO

After Hours Gainers:

Companies trading higher in after hours in reaction to earnings/guidance: None

Companies trading higher in after hours in reaction to news: PINS +14.2% (activist Elliott Mgmt has built a 9+% stake, according to WSJ), ZY +7% (expands agreement with Octant to further scale their platform), RCM +3.4% (to become exclusive provider of enterprise revenue cycle mgmt services for Sutter Health), RRGB +2.5% (names new CEO), DASH +1.8% (ABNB exec joins board), MGM +1.5% (GIGNY attracting takeover interest, MGM mentioned, according to Bloomberg), SPCE +0.8% (signs long-term lease for new manufacturing facility), R +0.6% (increases dividend), ILMN +0.4% (enters into settlement and license agreement with BGI Genomics), APA +0.1% (names new chairman)

After Hours Losers:

Companies trading lower in after hours in reaction to earnings/guidance: CDXS -21.3% (guides Q2 and FY22 revs below consensus; also signs deal with PFE to supply enzyme used in PAXLOVID), TXG -12.8% (guides Q2 revs below consensus), BTU -1% (guides Q2 revs below consensus), AOUT -0.7%

Companies trading lower in after hours in reaction to news: AUPH -4.1% (names new exec in R&D and new CCO), OMGA -2.1% (receives FDA clearance of its IND application to initiate a Phase 1/2 study of OTX-2002), CLOV -1.2% (to offer Medicare Advantage plans in 13 new counties), ABC -0.6% (awarded $6.065 bln contract from Defense Logistics Agency), GD -0.2% (awarded $908 mln US Air Force contract; also awarded $273 mln US Navy contract)