The Information : Microsoft’s Rivals Lean on AI to Pry Away Longtime Customers

Microsoft’s Rivals Lean on AI to Pry Away Longtime Customers

The Takeaway
• AI has made it cheaper to switch between enterprise software vendors
• Defense Department is testing AI to gain leverage over providers like Palantir
• Microsoft is offering AI to pry customers away from Salesforce, other competitors

Artificial intelligence has suddenly made it cheaper and easier for companies to switch to new software providers, IT executives say.

Now large AI providers such as Amazon, Microsoft, Salesforce and Palantir are scrambling to win over each other’s customers, who might previously have felt they were locked into using old apps because of the difficulty of extricating vast quantities of data. To solve that problem, the tech providers are selling or giving away new AI that writes code to move corporate data from one application to another or to reprogram old apps in newer formats.

For instance, federal agencies such as the Department of Defense have recently been testing AI models from Microsoft and OpenAI that aim to extract data from a wide range of analytics applications operated by contractors like Palantir and Lockheed Martin, according to one person who was involved in the tests and another person who was part of the negotiations.

Government officials hope these tools will give them leverage to negotiate better contracts with their current providers by threatening to move agency data to competing analytics apps, such as Microsoft’s Power BI, one of the people said.

It isn’t clear who will come out on top as enterprise app providers go after each other’s customers, but chief information officers say they’re already saving money as software switching costs fall. That’s especially true for older businesses that can use AI to move away from proprietary software sold by the likes of Microsoft or Salesforce in favor of open-source alternatives or competing apps.

‘AI Is Eating Software’

“We’ve heard that software will eat the world, and now AI is eating software,” said Viral Tripathi, chief information officer of C1, a Bloomington, Minn.–based company that sells more than $1 billion a year of software for managing office technology such as phones, servers and security systems.

Tripathi said his company has been using ChatGPT and other tools to write code for moving its data out of Microsoft Dynamics, which helps salespeople keep track of leads and customers, as the company switches to newer sales apps that automate more tasks.

He’s considering switching to Salesforce’s AI agent platform as well as similar tools offered by competing startups. He said C1 previously tried to develop an in-house alternative to Dynamics and Salesforce’s core customer relationship management app, but it wasn’t as good as the AI-infused tools Salesforce has since released.

Despite these threats, Microsoft has a plan of its own to use AI to snatch customers of competing sales apps.

Charles Lamanna, a Microsoft executive who oversees Dynamics and other back-office apps, said Microsoft is chasing customers that previously relied on sales apps from competitors like Salesforce but are now porting data to more rudimentary databases and using Microsoft tools to automate tasks such as generating emails. He declined to name the customers.

“Our own belief is in the next two years, you’ll probably delete more code than you’ve written around business apps and processes.…Instead of 100 custom [apps], you’ll just have a generative AI interface” in which customers tell the AI exactly what they want to do, he said.

Lamanna said Microsoft also believes it can capitalize on customer backlash to Salesforce’s policy restricting Slack customers from retrieving messages and files through competing AI apps they use.

Salesforce spokespeople did not have a comment.

In the past, moving databases by hand would have taken months of work by human engineers, but AI tools have cut that time in half.
Even as Palantir tries to beat back potential AI threats, the company says AI features of its data analytics software means it can replace apps such as Microsoft’s Power BI or back-office software from ServiceNow and SAP.

In recent months, Palantir has promised potential customers significant savings from canceling contracts with competing firms, according to someone who has been involved in the pricing negotiations.

Ditching Windows Servers

Other enterprise firms are giving away code-writing AI for free to help customers move data away from competitors’ apps or software.

Thomson Reuters, for instance, said it saved 30% on the cost of employees’ desktop software after using a new free AI tool from Amazon to rewrite the code powering Windows computers to Linux, an open-source operating system. That way, Thomson Reuters can run employees’ computers in Amazon’s cloud without incurring the Microsoft licensing fees that had made the company less willing to move its products to the cloud.

SonicWall, a 34-year-old cybersecurity firm, has been meaning to update its database software for years. But doing so always seemed like a time-consuming and laborious process—until this year, when AI tools became capable of automating the process.

Now SonicWall is planning to use AI software from Amazon and from the startup YugabyteDB to port data out of its old Microsoft SQL Server databases, which ran on the firm’s local servers and required paying licensing fees to Microsoft for maintenance.

In the past, moving the databases by hand would have taken months of work by human engineers, but the AI tools have cut that time in half, and the company expects to spend as much as 50% less to run the new SQL databases in the cloud, according to SonicWall Executive Vice President Denis Branco.

“We’re a 30-plus-year-old company with a lot of legacy technology, and historically there’s always been a monthslong runway to modernize before you get to the other side,” Branco said.

“With AI, it moves a lot faster.”

The Information : The Electric: A Battery CEO on Robots—'They Need a Lot of Powe

The Electric: A Battery CEO on Robots—'They Need a Lot of Power'

Kang Sun is out to bust up a battery industry consensus. For years, battery startups have assumed that to succeed they needed to penetrate at least one of three big industries: electric vehicles, stationary storage or portable electronics.

But Sun, CEO of silicon anode developer Amprius Technologies, notes that the pursuit of those industries hasn’t gone very well: A couple of startups have sold their batteries to a fitness device company or two, along with some Chinese-made smartphone makers. But no startup’s batteries are powering any commercial EV; carmakers, instead of adopting new chemistries, have stayed with “good enough” conventional batteries that cost less. And the market for stationary storage batteries is dominated by cheap, low-end batteries largely made in China.

Sun argues, however, that there is enough business outside those industries to create a healthy company. One vibrant future market, he says, is electric aviation, including drones, high- and low-orbiting satellites, and electric flying taxis. Other markets are artificial intelligence data centers and robots.

“Aviation is a big market, actually. It’s growing very, very fast,” Sun told me. “I went to one country. I cannot mention which one. Their vice president told me they need—this is a small country, very small—three million drones. You can imagine.”

As for robots, he says, “They walk. They lift weight. So they need a lot of power.”

There is an investment boom in all the areas Sun cites: The wars in Russia, Ukraine and Israel have created a surge of interest in military drones. And one of Elon Musk’s latest ventures—the Optimus robot—has ignited a similar rush of investor interest in humanoid robots. Both drones and robots require high energy density to run for a long time, as well as high power to land and move fast—the very needs advanced battery startups can address.

Since drones and robots—unlike cars and electronic devices—have not been around a long time, they by and large do not have the same scale of dug-in incumbent companies with longstanding suppliers. And, unlike the consumer car industry, they are not—at least yet—brutally competitive industries that squeeze every last penny out of suppliers. That leaves room for nimble battery startups—whose batteries are often costly—to break in.

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The Trump administration is encouraging them to do so. For instance, China’s DJI dominates the manufacture of drones and drone components, so the Pentagon has made it a priority to quickly build up U.S. drone-making capacity, creating urgency for the batteries that will power them.

Last week, Fremont, Calif.-based Amprius said it had shipped a new generation of prototype batteries meant for long-distance drone flights to an Airbus subsidiary. Sun said these batteries deliver energy density of 450 watt-hours per kilogram, more than 50% greater than virtually anything else sold commercially. That means Amprius batteries can carry a drone much further.

Sun said the company had separately shipped batteries to multiple drone makers that can deliver an also impressive 370 Wh/kg of energy. These were tweaked to deliver that energy fast, which is needed if you are stopping in midair to take a peek at a Russian platoon, or loitering in the sky for hours or days at a time.

Most drone batteries available today, if they can push out power that fast, offer just 200 Wh/kg of energy, said Spencer Gore, a drone expert.

Amprius, founded in 2008 by a Stanford University professor, went public in 2022 in a reverse merger. As we reported last week, its shares have been on a tear, surging more than 200% since the beginning of June.

Sun said that at first when he became CEO in 2017, he tried to break into all three segments. He found that stationary storage was a nonstarter because the price the battery systems makers were prepared to pay to suppliers was so low “it’s like it’s for free.”

EV makers take too long to test the batteries of new suppliers, he said, and even if Amprius got an EV deal, it would need to scale production dramatically if it wanted to turn a profit, an ultraexpensive proposition. “If your battery factory isn’t making a quarter-million EVs, you’re going to make no money at all,” he said.

As for electronics devices, they are dominated by big companies like Apple and Samsung that have largely used the same suppliers for years, he said. “Do you think Apple is going to use an Amprius battery tomorrow?” Sun said.

But the military is prepared to pay top dollar for drone batteries. For niche military applications, batteries can command $1,500 to $3,000 per kilowatt-hour, far more than the $100/kWh carmakers pay for EV batteries.

However, you still have to think big because drones alone are too small a business for a company that has been focused on EV demand.

Gene Berdichevsky, CEO of silicon anode developer Sila Nanotechnologies, took me through the math. Until last year, apart from dabbling in fitness devices, he was ignoring any market but EVs because he didn’t have any additional production capacity on his pilot line. Now, he is hoping for drone orders.

One thing he has quickly understood is that he would have to sell a lot of drone batteries to make them count on his bottom line: Say he got an order for what a major carmaker would consider a small vehicle line—100,000 cars a year. With a 100 kWh battery in each EV, that would be 10 gigawatt-hours of production, Berdichevsky said.

Then take a typical civilian drone that you might fly for taking aerial photos—it might have 100 watt-hours, or about a thousandth the capacity of an EV battery.

“So if you have an auto contract for a tiny program of 100,000 cars, that will be like a 100 million drones for the same production capacity, which is more than all the drones ever made,” Berdichevsky said. “So while you’re touching these high prices for drone batteries, that’s great, but the volumes are small.”

In other words, if you could actually get a contract to supply batteries for a million EVs a year, you would have a grand slam. If you sold a million drone batteries, you would probably rate that a solid single.

So Sun argues that when you’re tackling aviation, you need to think broader than drones. Since 2018, for instance, Amprius has sold high-power cells to Airbus for surveillance satellites. He is also going after air taxis, known as electric vertical takeoff and landing aircraft, or eVTOLs.

He has also found that stationary storage is a big business, and not monolithic: AI data centers are their own segment, and even the data centers comprise different battery segments.

One requirement of data centers is backup power—batteries that store the electricity gathered by solar panels or wind turbines and deliver it when it’s needed, such as at night, when the sun is no longer shining. The go-to backup batteries are the same cheap, low-end lithium-iron-phosphate batteries—mostly made in China—that utilities use on the grid, and that Tesla employs in its home Powerwalls. No operation in its right mind would use an expensive advanced battery for this purpose.

AI data centers also require surges of power, Sun said: Unlike homes and offices, data centers attempt to avoid any dip in power because their operations are ultraexpensive. That makes them a market for batteries like Amprius’ that can provide a long and fast dollop of power until grid or other base power is restored.

I asked Sun whether all these strands of businesses together—drones, satellites, robots, AI data centers and so on—could comprise a reasonable business. He said they could. “Many of the startups,” he said, “are changing their direction now.”

“Those are the markets Amprius is focusing on,” he said. “I think we placed the right bet a couple of years ago.”

>>> US Gapping down

Gapping down
In reaction to earnings/guidance
:
  • RVTY -7.4% ( beats by $0.04, beats on revs; lowers FY25 EPS guidance; raises FY25 revenue guidance ).
Other news:
  • ATAI -9.5% ( Recognify life sciences provides Update on Phase 2b Trial of Inidascamine in patients with cognitive impairment associated with Schizophrenia ).
  • ARLP -4% (Reports Second Quarter Financial and Operating Results; Declares Quarterly Cash Distribution of $0.60 Per Unit; and Updates 2025 Guidance ).
  • ACTU -2.2% (files for 1,332,994 share common stock offering by selling shareholders).
  • TNXP -1.4% ( provides operations update ).
  • CNP -1.3% (announces offering of $900 mln of Convertible Senior Notes due 2028 in a private placement ).
  • SRPT -1% ( FDA investigating the death of an 8-year-old boy who received Elevidys, D.E. Shaw disclosed increased stake of 5.1% (more than 5 mln shares, previously disclosed 4.4K shares) ).
  • NWBI -1% ( completes acquisition of Penns Woods Bancorp (PWOD).

>>> US Gapping up

Gapping up
In reaction to earnings/guidance
:
  • BOH +1.5% (reports EPS in-line).
Other news:
  • CELC +216.2% (announces clinically meaningful improvement in both progression-free survival primary endpoints from PIK3CA wild-type cohort of phase 3 VIKTORIA-1 trial Cohort from the Phase 3 VIKTORIA-1 trial ).
  • NA +9.1% ( announced a significant increase of its BNB holdings to 128,000 tokens).
  • ZYME +8.5% ( announces FDA clearance of investigational new drug application for ZW251, a novel glypican 3-targeted topoisomerase 1 inhibitor antibody-drug conjugate ).
  • BTCS +8.3% ( announces the successful closing of its issuance of approximately $10 million in above marked convertible notes).
  • WRD +7.8% (WeRide's Robotaxi was granted Saudi Arabia's first Robotaxi autonomous driving permit ).
  • CMCM +7.1% ( to acquire controlling stake in UFACTORY to accelerate its robotics commercialization strategy).
  • NICE +6.4% (announced that it has entered into a definitive agreement to acquire Cognigy, a global market leader in conversational and agentic AI. ).
  • USM +3.8% ( discloses in SEC filing that it appointed Douglas Chambers as interim President and CEO contingent and effective upon the closing of the transactions contemplated by certain Securities Purchase Agreement by and among Telephone and Data Systems (TDS)).
  • TE +2.8% ( strategy supported by Section 232 polysilicon and AD/CVD investigations).
  • JG +2.7% (announced that its AI agent platform GPTBots.ai will integrate Grok 4, an advanced large language model ).
  • BMRN +2.7% ( announces the successful closing of its issuance of approximately $10 million in above marked convertible notes).
  • SUPX +2.6% (announced a major strategic expansion with the planned establishment of its first regional supply center in Japan ).
  • KZIA +1.8% ( entered into an At the Market Offering Agreement ).
  • CIFR +1.7% ( confirmed Bitfury mutually terminated observer agreement).
  • LIMN +1.7% ( announces plans for expansion into cryptocurrency and blockchain sector; Targets up to $500 mln in investments for BNB Coin).
  • TSLA +1.6% ( CEO Elon Musk says "Samsung's (SSNLF) giant new Texas fab will be dedicated to making Tesla's next-generation AI6 chip; agreement worth $16.5 bln ).
  • KKR +1.6% ( launches tender offer for Topcon ).
  • EU +1.6% (announces continued positive uranium extraction rates; promotes Mr. Dain McCoig to COO).
  • ACHR +1.4% ( disclosed ruling on motions to dismiss stockholder class action ).
  • NNE +1.1% ( files for $620 mln mixed securities shelf offering).
  • SATL +1.1% (Hannover Holdings S.A. lowered active stake to 5.7% (prior 6.8%)).

WWD : Moncler Grenoble to Hold Fall Show in Aspen

Moncler Grenoble to Hold Fall Show in Aspen
To be staged on Jan. 31, this will be the first American ski destination show for the brand.

MILAN — Moncler Grenoble is heading to the U.S. for its next outdoor showcase.

The brand’s fall 2026 collection will be unveiled in Aspen, Colo., on Jan. 31 next year. This is the first American ski destination show for the brand.

In March, Moncler Grenoble traveled to Courchevel, the French Alps ski resort located in the Tarentaise Valley. Anne Hathaway, Adrien Brody, Jessica Chastain, Penn Badgley and Brooklyn Beckham, among others, attended the show, which was staged amid a blizzard at the Courchevel Altiport, Europe’s highest airport at 6,588 feet.

In February last year, the brand held its fall 2024 show in Saint Moritz and chairman and chief executive officer Remo Ruffini said at the time that he saw itinerant shows as the future of Grenoble, which are aimed at heightening its visibility.

As reported, Moncler revenues in the Americas were flat at 147.9 million euros in the first half of the year, but in the second quarter, they rose 5 percent at constant exchange, accelerating compared with the previous quarter mainly thanks to the sequential improvement registered in the direct-to-consumer channel.

Commenting on the performance, Gino Fisanotti, Moncler’s chief brand officer, highlighted the “U.S.-oriented initiatives” in the period, ranging from the brand’s first participation at the Met Gala in May to the Moncler Genius collection with Mercedes-Benz by Nigo and the first collection of apparel collaborating with Donald Glover’s Gilga Farm unveiled in June, among others. Fisanotti also said Moncler Grenoble was “the fastest growing” in the period.

Moncler Grenoble owes its name to the city that hosted the Olympic Games in 1968, when the brand was the French national ski team’s official supplier. The first Grenoble collection was presented in New York in January 2010 during the city’s fashion week.

In 2022, Moncler rebooted Grenoble as the brand’s “high-performance” division, flanked by the fashion-forward Moncler Genius line and the lifestyle Moncler Collection.

FT : Volkswagen embodies the challenge ahead for European industry

Volkswagen embodies the challenge ahead for European industry
The risks of decline go far beyond any single company

Europe’s automakers face mounting problems. For over a decade, an industry historically associated with technological and engineering excellence has concealed less flattering truths about high costs and stagnating output. Now faced with a trade conflict and accelerating Asian rivals, the ability of Volkswagen and others to restructure is a litmus test for whether European industry can remain globally relevant.

Our company embodies the challenge ahead. For too long we have operated under the assumption that growth would offset rising costs and underutilised capacity. Fuelled by profits from China and strong sales of premium brands such as Porsche and Audi, Volkswagen tried to grow its way out of the problem instead of addressing structural inefficiencies. When demand softened, the consequences became clear — declining margins, idle factories, and fast-moving rivals first from the US and now China grabbing share on their home turf.

But this is not just Volkswagen’s challenge. The auto industry remains a pillar of Europe’s economy. According to McKinsey, manufacturers, suppliers, finance providers and after-sale care services together account for 7 per cent of Europe’s GDP and support nearly 14mn jobs across the continent. The sector also drives wider growth: every euro invested generates more than twice that in added value in the broader economic landscape. The risks of decline go far beyond any single company.

Carmakers’ woes also reflect a deeper, long-term issue: Europe’s widening productivity gap. Over the past 25 years, labour productivity growth in the US has outpaced that of Europe by at least a percentage point on average per year. Today, the consequences are stark. According to Goldman Sachs, labour productivity per person employed in the US is, adjusted for purchasing power, between 35 and 45 per cent higher than in France, Germany and the UK — and the divide continues to grow.

Volkswagen Group is confronting these challenges head-on with tough decisions. We have reduced production capacity by 750,000 automobiles in our German plants. We have limited wage growth. And we are reducing our workforce by 35,000 in Germany alone by 2030 to boost productivity both in terms of labour and capital. These steps are not easy, but they are necessary in a world where competitiveness is non-negotiable. At the same time, we are investing decisively in the future, allocating €165bn over the next five years to drive electrification and digitalisation while expanding into areas such as autonomous driving.

But one thing has become clear: investment alone is not enough. Structural reform must come first — both at Volkswagen and in the European Union. Without changing how we work, build and organise, even the boldest investments will fall short. Long-term industrial competitiveness depends on core efficiency.

Priority reforms for the EU include more flexible labour markets and smarter regulation that supports rather than stifles innovation. It also means being pragmatic: securing access to critical raw materials and adopting technology partnerships where speed matters more than self-sufficiency. That’s why Volkswagen and others have entered tech-focused joint ventures with partners in China and North America. The goal: to speed up development of software, architecture, and platforms — while scaling faster and reducing costs, instead of building everything in-house.

All of this requires more ambition. Europe must become a place where bold ideas are not just researched but industrialised and scaled up across a common market. “Profit” should not be something we need to excuse. It is the foundation for a sustainable business model and for securing jobs and prosperity.

There has been some progress. The Draghi report on European competitiveness set the right tone. But speed and scale remain lacking. One example: EU battery regulations due to be advanced this year risk imposing costs and complexity that disadvantage local producers. Given that batteries account for the single largest part of an electric vehicle’s cost, this is not just a technicality — it’s a strategic issue.

At Volkswagen, we’ve embarked on change, and the initial results are promising. But the road ahead is long and winding. The ingredients for Europe’s renewal exist, too. What made the continent strong in the first place — a passion for innovation, a commitment to education, a culture of performance — should be its guiding values. To move forward, we must now choose structural reform over complacency, performance over nostalgia, and bold adaptation over rigid tradition. The future of European industry depends on it.

>>> US Research Calls I

Research Calls I
  • Upgrades
    • Alector (ALEC) upgraded to Outperform from Neutral at Mizuho, tgt $3.50
    • Broadstone Net Lease (BNL) upgraded to Outperform from Peer Perform at Wolfe Research, tgt $19
    • Charter (CHTR) upgraded to Outperform from Market Perform at Bernstein, tgt $380
    • Hesai (HSAI) upgraded to Overweight from Equal Weight at Morgan Stanley, tgt $26
    • Mara Holdings (MARA) upgraded to Overweight from Neutral at JPMorgan, tgt $22
    • Netstreit (NTST) upgraded to Neutral from Underperform at BofA
    • Nike (NKE) upgraded to Overweight from Neutral at JPMorgan
    • PagerDuty (PD) upgraded to Buy from Hold at TD Cowen
    • Texas Instruments (TXN) upgraded to Outperform from Peer Perform at Wolfe Research
    • Textron (TXT) upgraded to Neutral from Sell at UBS, tgt $88
    • USCB Financial (USCB) upgraded to Outperform from Market Perform at Raymond James, tgt $20
    • Weatherford (WFRD) upgraded to Overweight from Neutral at Piper Sandler, tgt $73
  • Downgrades
    • American Eagle (AEO) downgraded to Underweight from Neutral at JPMorgan, tgt $9
    • BHP Group (BHP) downgraded to Market Perform from Outperform at BMO Capital
    • Bilibili (BILI) downgraded to Neutral from Overweight at JPMorgan, tgt $24
    • CapsoVision (CV) downgraded to Neutral from Buy at Guggenheim
    • Centene (CNC) downgraded to Neutral from Overweight at Cantor Fitzgerald, tgt $38
    • Cisco (CSCO) downgraded to In Line from Outperform at Evercore ISI, tgt $72
    • Core & Main (CNM) downgraded to Hold from Buy at Loop Capital, tgt $68
    • First Citizens (FCNCA) downgraded to Neutral from Overweight at Piper Sandler, tgt $2,150
    • GE Vernova (GEV) downgraded to Neutral from Buy at Guggenheim
    • GE Vernova (GEV) downgraded to Neutral from Outperform at Mizuho, tgt $670
    • Halliburton (HAL) downgraded to Neutral from Overweight at Piper Sandler, tgt $25
    • HCA Healthcare (HCA) downgraded to Peer Perform from Outperform at Wolfe Research
    • IREN (IREN) downgraded to Neutral from Overweight at JPMorgan, tgt $16
    • NetEase (NTES) downgraded to Neutral from Overweight at JPMorgan, tgt $140
    • Quanta Services (PWR) downgraded to Market Perform from Outperform at Bernstein, tgt $410
    • Remy Cointreau (REMYY) downgraded to Underweight from Equal Weight at Barclays
    • Riot Platforms (RIOT) downgraded to Neutral from Overweight at JPMorgan, tgt $15
    • Sarepta (SRPT) downgraded to Underweight from Equal Weight at Barclays, tgt $10
    • Synovus (SNV) downgraded to Market Perform from Outperform at Raymond James
    • Teck Resources (TECK) downgraded to Neutral from Buy at B. Riley
    • Tenet Healthcare (THC) downgraded to Peer Perform from Outperform at Wolfe Research
    • Titan America (TTAM) downgraded to Hold from Buy at Stifel, tgt $15
    • TRI Pointe (TPH) downgraded to Peer Perform from Outperform at Wolfe Research
  • Others
    • Accenture (ACN) initiated with a Reduce at HSBC, tgt $240
    • Allarity (ALLR) initiated with a Buy at Ascendiant, tgt $9
    • Almonty (ALM) initiated with a Buy at Alliance Global Partners
    • Ares Management (ARES) initiated with a Market Perform at Raymond James
    • Blue Owl Capital (OWL) initiated with a Market Perform at Raymond James
    • CapsoVision (CV) initiated with a Buy at Roth Capital, tgt $6
    • CapsoVision (CV) initiated with a Speculative Buy at Benchmark
    • CleanSpark (CLSK) initiated with a Buy at Ladenburg
    • CoastalSouth (COSO) initiated with an Overweight at Piper Sandler, tgt $26
    • Electronic Arts (EA) initiated with an Equal Weight at Wells Fargo, tgt $168
    • Enanta (ENTA) assumed with a Buy at H.C. Wainwright
    • Fold Holdings (FLD) initiated with an Overweight at Cantor Fitzgerald
    • Gold Fields (GFI) initiated with a Buy at Canaccord, tgt $33
    • Horace Mann (HMN) initiated with an Outperform at BMO Capital, tgt $48
    • Innate Pharma (IPHA) initiated with a Buy at BTIG, tgt $8
    • Intensity Therapeutics (INTS) initiated with a Buy at ThinkEquity
    • Lionsgate Studios (LION) initiated with a Buy at Benchmark
    • MongoDB (MDB) initiated with an Outperform at BMO Capital, tgt $280
    • MoonLake (MLTX) initiated with a Neutral at Rothschild & Co Redburn, tgt $65
    • Surgery Partners (SGRY) resumed with a Buy at BofA
    • Semler Scientific (SMLR) initiated with an Overweight at Cantor Fitzgerald
    • Take-Two (TTWO) initiated with an Overweight at Wells Fargo, tgt $265
    • Ultragenyx (RARE) assumed with a Buy at H.C. Wainwright
    • Vertiv (VRT) initiated with an Outperform at William Blair
    • Wave Life Sciences (WVE) initiated with an Outperform at Oppenheimer, tgt $24

Celcuity announces clinically meaningful improvement in both progression-free su

Celcuity announces clinically meaningful improvement in both progression-free survival primary endpoints from PIK3CA wild-type cohort of phase 3 VIKTORIA-1 trial
  • Gedatolisib + palbociclib + fulvestrant ("gedatolisib triplet") reduced the risk of disease progression or death by 76% vs. fulvestrant (HR=0.24; 95% CI: 0.17--0.35; p<0.0001). Median PFS was 9.3 months with the gedatolisib triplet versus 2.0 months with fulvestrant
  • Gedatolisib + fulvestrant ("gedatolisib doublet") reduced the risk of progression or death by 67% vs. fulvestrant (HR=0.33; 95% CI: 0.24--0.48; p<0.0001). Median PFS was 7.4 months with the gedatolisib doublet versus 2.0 months with fulvestrant
  • The efficacy results establish several new milestones in the history of drug development for HR+/HER2- advanced breast cancer
  • Treatment discontinuation due to a treatment-related adverse event for the gedatolisib triplet and gedatolisib doublet was lower than was observed in Arm D of Celcuity's Phase 1b trial in ABC patients and lower than observed in any Phase 3 trials for currently approved drug combinations in HR+/HER2- ABC
  • The favorable safety profile with the gedatolisib triplet and gedatolisib doublet was better than observed in the Phase 1b trial in ABC, including lower rates of hyperglycemia and stomatitis
  • Full data from the PIK3CA wild-type cohort of the VIKTORIA-1 clinical trial will be presented at an upcoming medical conference later this year. Celcuity expects to submit a New Drug Application for gedatolisib to the U.S. Food and Drug Administration in the fourth quarter of 2025. Topline data for the VIKTORIA-1 PIK3CA mutation cohort is expected by the end of 2025.

>>> Europe : Brokers Upgrades & Downgrades - 28th of July 2025 V3(++)

>>> Up
* Alimak PT Raised to 180 kronor from 152 kronor at Berenberg
* AMS-Osram Raised to Hold at Research Partners (++)
* Burberry PT Raised to 1,600 pence from 1,250 pence at Citi
* Drax Raised to Neutral at Citi; PT 682 pence
* Iberdrola Raised to Add at AlphaValue/Baader (++)
* Incap Raised to Accumulate at Inderes; PT 12 euros
* Italgas Raised to Buy at Intesa Sanpaolo; PT 7.80 euros (+)
* Kone PT Raised to 67 euros from 65 euros at Bernstein
* Landis + Gyr Raised to Buy at Berenberg; PT 80 Swiss francs
* Mapfre Raised to Add at AlphaValue/Baader
* Nike Raised to Overweight at JPMorgan; PT $93 (++)
* Oklo Raised to Outperform at Daiwa; PT $86
* Quilter Raised to Hold at Deutsche Bank; PT 165 pence
* Reply Raised to Outperform at Oddo BHF; PT 178 euros (+)
* Sartorius Raised to Outperform at Bernstein; PT 272 euros (+)
* Texas Instruments Raised to Outperform at Wolfe; PT $230 (++)

>>> Down
* Entain Cut to Hold at Investec; PT 1,040 pence
* Julius Baer Cut to Equal-Weight at Barclays
* Kalmar Cut to Hold at SEB Equities; PT 42 euros
* Kalmar Cut to Neutral at BNPP Exane; PT 38 euros (+)
* Kuehne + Nagel Cut to Add at AlphaValue/Baader
* Loomis Cut to Hold at SEB Equities; PT 450 kronor
* Puma Cut to Underperform at BNPP Exane; PT 15 euros
* Puma Cut to Hold at Deutsche Bank; PT 20 euros
* Puma Cut to Hold at mwb research AG; PT 22 euros (++)
* Remy Cointreau Cut to Underweight at Barclays; PT 45 euros
* Remy Cointreau Cut to Hold at TP ICAP Midcap; PT 67 euros (++)
* Repsol Cut to Neutral at CaixaBank BPI; PT 15.20 euros (++)
* Richemont Cut to Hold at HSBC; PT 158 Swiss francs
* RS Group Cut to Underperform at BNPP Exane; PT 480 pence
* Swatch Cut to Reduce at HSBC; PT 113 Swiss francs
* Titan America Cut to Hold at Stifel; PT $15
* Vontobel: ODDO BHF SCA abaisse à 62 (66) CHF - neutral (+)

>>> Initiation
* Electronic Arts Rated New Buy at Freedom Capital; PT $185 (++)
* Faron Pharma Rated New Buy at Stifel; PT 371.31 pence (++)
* NXP Semi Rated New Outperform at Baptista Research; PT $262.40
* Pony AI ADRs Rated New Buy at Daiwa; PT $20

>>> Call
* Burberry Execution is on Track, Target Set to Joint-High at Citi
* Deutsche Bank Strategists Say Equity Exposure Rose Last Week (++)
* Drax Loses Only Sell as Citi Sees ‘Strategic Breathing Room’
* Forvia Results Strong Considering Tough Backdrop, Jefferies Says (+)
* Landis+Gyr Raised to Buy at Berenberg on Divestment Catalyst
* Morgan Stanley Reiterates That S&P 500 Bull Case Is Solidifying (++)
* Oppenheimer Lifts S&P 500 Target to Street-High on Trade Deals (++)
* Titan America Cut to Hold at Stifel on Slower Housing Activity (++)
* Watch Aerospace in Wake of Positive US-EU Deal: Morgan Stanley