>>> JPM Healthcare Conference San Francisco

JPM European Pharma & Biotech names will present over four days at the J.P. Morgan Healthcare Conference (Jan 12–15, 2026, all times PST), with M&A firepower and BD optionality a core cross‑stock theme. Below is a concise calendar plus key M&A‑relevant angles in a Bloomberg‑style note.

Conference calendar (PST)
Monday, Jan 12
  • 07:30 – GSK
  • 08:15 – Argenx
  • 09:00 – Novartis
  • 09:45 – Sanofi
  • 11:15 – Merck KGaA
  • 13:30 – Galderma
  • 14:15 – Oxford Nanopore
  • 15:00 – Roche
Tuesday, Jan 13
  • 07:30 – GSK (listed under Tuesday in schedule table, but also shown in header as Tuesday presenter; handbook table aligns with GSK at 07:30)
  • 09:00 – AstraZeneca
  • 09:45 – Novo Nordisk / Sandoz
  • 10:30 – Lonza
  • 11:15 – Bayer
  • 13:30 – Zealand
  • 15:45 – Genmab
  • 16:30 – Ipsen
Wednesday, Jan 14
  • 07:30 – UCB
  • 11:15 – Recordati
  • 13:30 – Zealand (as per main schedule table)
  • 15:00 – Bachem
Thursday, Jan 15
  • 10:30 – Molecular Partners
(Grifols has no conference presentation; Oxbio and various small caps are covered in the handbook but not in the core EU pharma schedule table.)

Cross‑sector M&A setup
  • Large‑cap firepower remains substantial: JPM estimates EU large caps have sizeable deal capacity at 3.0x 2025E Net Debt/EBITDA, led by Roche, Novartis, Novo, Sanofi, Bayer and Merck, reinforcing scope for structured BD and bolt‑ons rather than mega‑mergers.
  • Post‑2030 patent cliff drives external growth: Report explicitly flags “firepower” as increasingly important as EU large caps look beyond 2030, keeping M&A and in‑licensing at the centre of equity stories into and beyond JPM week.

Name‑by‑name M&A / BD angles
Novartis (Mon 09:00)
  • Balance sheet and firepower charts place Novartis among the group with significant headroom at ~3x 2025E Net Debt/EBITDA, underpinning continued BD optionality.
  • Pipeline grid highlights multiple late‑stage assets (pelacarsen, zigakibart, del‑desiran, abelacimab, del‑zota, del‑brax), tilting strategy toward targeted bolt‑on deals and licensing to complement in‑house programs rather than transformational M&A.
Sanofi (Mon 09:45)
  • Sector section emphasises the need to supplement organic amlitelimab and immunology build‑out with externally sourced assets as Sanofi manages high‑single‑digit EPS ambitions and FX headwinds.
  • AATD and immunology readouts plus continued focus on specialty care keep Sanofi positioned as both a buyer (immunology, rare disease) and occasional partner of choice.
Merck KGaA (Mon 11:15)
  • JPM explicitly flags potential “corporate” moves including a partnership announcement for precemtabart tocentecan (M9140) and “potential M&A / business development in Life Sciences.”​
  • Disposal of Surface Solutions and acquisition of SpringWorks reshape the portfolio; 2026 guidance discussion links FX and BD to EBITDA trajectory, signalling ongoing portfolio reshuffling rather than scale M&A.
Roche (Mon 15:00)
  • High absolute firepower and relatively moderate leverage (Net Debt/EBITDA) place Roche at the top end of EU large‑cap deal capacity.JPM_European_Pharma-Conference-Book-1.pdf​
  • Obesity, neurology and hematology assets (petrelintide, CT‑996, CT‑388, Evrysdi combinations) are highlighted as pipeline pillars, with external innovation likely to remain a lever to sustain growth vs. consensus.JPM_European_Pharma-Conference-Book-1.pdf​
GSK (Tue 07:30)
  • Guidance narrative focuses on managing U.S. vaccine pricing headwinds and investing into oncology and respiratory; M&A frame is more selective, with emphasis on targeted assets rather than large scale deals.JPM_European_Pharma-Conference-Book-1.pdf​
  • Newsflow list includes a potential Capital Markets Day for the new CEO strategy in 3Q26, where M&A / BD framework will likely be a key topic.
AstraZeneca (Tue 09:00)
  • Strong 2025‑30 growth profile but still reliant on external innovation in oncology and rare disease; multiple pivotal datasets (Dato‑DXd, AZD0901, camizestrant, eplontersen) reduce urgency for large M&A but support bolt‑on appetite using balance‑sheet headroom.
  • Cardiometabolic and obesity adjacency (Eplontersen, etc.) positions AZN as a logical future consolidator in cardiometabolic and genetic disease platforms.​
Novo Nordisk (Tue 09:45)
  • Obesity and diabetes cash flows underpin significant theoretical deal capacity, but handbook stresses focus on internal obesity pipeline (CagriSema, Amycretin, ziltivkemab) and competitive dynamics vs. Lilly rather than large M&A.
  • BD read‑through is more about tuck‑ins or technology deals that extend GLP‑1/GIP/tri‑agonist leadership.
Bayer (Tue 11:15)
  • One of the larger firepower contributors, but litigation overhang (glyphosate, dicamba) constrains near‑term big‑ticket M&A.
  • JPM frames Bayer as a positive catalyst watch into asundexian OCEANIC‑Stroke data and multiple litigation milestones, implying any sizeable M&A is more a medium‑term option once legal visibility improves.
Lonza (Tue 10:30)
  • Mid‑cap CDMO strongly positioned as a target of pharma outsourcing wallets; JPM highlights CDMO‑driven growth with margin expansion and specific 2026 newsflow around Vacaville contracting and CHI divestment.
  • Strategic narrative is about portfolio optimisation (divest CHI, add capacity/tech via smaller deals) rather than selling the group or pursuing large acquisitions.
Galderma (Tue 13:30)
  • Aesthetics and dermatology growth plus Ipsen arbitration around a terminated early‑stage R&D collaboration underscore BD intensity in the space.
  • Guidance assumptions include continued investment in commercial and R&D, suggesting scope for further bolt‑on brand/asset deals while keeping leverage in check.
Genmab (Tue 15:45)
  • Heavy reliance on partnered programs (Darzalex, Kesimpta, Epkinly) positions Genmab structurally as a BD platform story, but JPM’s cuts to 2026 EPS vs. consensus underscore the execution risk.
  • 2026‑27 data (Epkinly 1L DLBCL, petosemtamab) could be triggers for broader strategic interest from large caps seeking antibody / bispecific know‑how.
Ipsen (Tue 16:30)
  • Ipsen explicitly flagged with potential 2026 “M&A to add to the pipeline,” alongside a potential update on the Galderma arbitration.
  • With expected 2026 core margin at ~30% and growth skewed to specialty, Ipsen screens both as an acquirer of late‑stage specialty assets and as a mid‑cap consolidation candidate.
UCB (Wed 07:30)
  • Catalyst watch name with firepower focused on immunology and neurology; handbook emphasises 2025‑30 EPS CAGR and need to keep replenishing the portfolio.
  • Donzakimig, Rystiggo and Bimzelx data frame UCB more as a bolt‑on acquirer / licensing player than a large take‑out target in the near term.
Recordati (Wed 11:15)
  • Explicit “potential further M&A / BD update on CVC stake” flagged in 2026 newsflow, putting capital allocation and deal appetite on the agenda.
  • Expected revenue and EBITDA ranges for 2026 leave room for targeted rare‑disease or specialty additions, consistent with its historical BD footprint.
Zealand (Wed 13:30)
  • Obesity pipeline (petrelintide, survodutide, CT‑388) dominates NPV and is co‑developed with a partner, making Zealand a structurally strategic mid‑cap in the obesity M&A theme.
  • JPM models large royalty streams and partnership economics, implicitly positioning the name as both a partner and a potential take‑out once Phase II/III risk clears.
Bachem (Wed 15:00)
  • Peptide / oligo CDMO with strong growth; 2026 newsflow items include new CEO strategy and continued emphasis on investments and contracts in GLP‑1 and peptide supply.
  • Strategically, Bachem sits in the “scarce assets” bucket for large‑cap buyers wanting secure GLP‑1/API supply, even if JPM does not explicitly flag live M&A.
Oxford Nanopore (Mon 14:15)
  • 2026 commentary highlights likely trading update at JPM and FY25 guidance, with emphasis on ONT and peer commentary; no explicit M&A flag, but technology remains highly strategic for genomics players.
Molecular Partners (Thu 10:30)
  • Handbook very explicit on partnering strategy: MP0533 in AML is expected to be out‑licensed if Phase I data are positive, with modelled 500m peak sales and 20% royalties.
  • MP0712 (DLL3 radio‑DARPin) and MP0726 (MSLN radio‑DARPin) are positioned for BD (partnering milestones, royalties), making JPM framing clearly “platform for out‑licensing” rather than stand‑alone fully integrated biotech.

How to trade the M&A angle into JPM
  • Buy firepower + need: Roche, Novartis, Sanofi, Bayer, Merck and AZN screen as best‑placed to deploy balance sheets against mid‑cap and platform stories; JPM firepower charts support this view.JPM_European_Pharma-Conference-Book-1.pdf​
  • Key “assets for sale” narratives: Lonza, Bachem, Zealand, Oxford Nanopore and Molecular Partners are portrayed as structurally positioned to monetise technology via partnerships or, longer term, strategic interest from larger buyers.

>>> Europe : Brokers Upgrades & Downgrades - 9th of January 2026 V2(+)

>>> Up
* Airbnb Raised to Equal-Weight at Wells Fargo; PT $128
* Airbnb Raised to Equal-Weight at Barclays; PT $120
* Altri Raised to Outperform at Grupo Santander; PT 5.49 euros
* Altria Raised to Buy at UBS; PT $63
* Antofagasta Raised to Buy at Goldman; PT 4,000 pence
* Auto Trader Raised to Equal-Weight at Morgan Stanley
* Balfour Beatty PT Raised to 800 pence at Berenberg (+)
* BNP Paribas Raised to Overweight at JPMorgan; PT 102 euros
* Cleveland-Cliffs Raised to Overweight at Morgan Stanley; PT $17
* Costain PT Raised to 190 pence from 175 pence at Berenberg (+)
* CrowdStrike Raised to Buy at Berenberg; PT $600
* L'Oreal Raised to Buy at UBS; PT 430 euros
* Marriott Intl Raised to Outperform at BMO; PT $370 (+)
* Marks & Spencer Raised to Buy at Berenberg; PT 415 pence
* Norske Skog Raised to Buy at Pareto Securities; PT 25 kroner
* Scout24 Raised to Overweight at Morgan Stanley; PT 114 euros
* SMG SW Raised to Overweight at Morgan Stanley

>>> Down
* AB Foods Cut to Hold at Shore Capital (+)
* Alcon AG Cut to Hold at Stifel; PT 63.96 Swiss francs
* Aviva Cut to Equal-Weight at Morgan Stanley; PT 670 pence
* BE Semiconductor Cut to Hold at Kepler Cheuvreux
* BMW Cut to Underweight at Barclays; PT 82.50 euros
* Cellnex Cut to Neutral at Goldman; PT 31 euros
* GE Vernova Cut to Neutral at Baird; PT $649
* Hannover Re Cut to Equal-Weight at Morgan Stanley; PT 270 euros
* Herantis Pharma Cut to Reduce at Inderes; PT 2.50 euros
* M&G Cut to Equal-Weight at Morgan Stanley; PT 285 pence
* Mattel Cut to Neutral at Goldman; PT $21 (+)
* Metso Cut to Neutral at BofA
* Nucor Cut to Equal-Weight at Morgan Stanley; PT $180
* Porsche Cut to Underweight at Barclays; PT 40 euros
* Rightmove Cut to Underweight at Morgan Stanley; PT 510 pence
* Sandvik Cut to Neutral at BofA
* Sartorius Stedim Cut to Sector Perform at RBC; PT 240 euros
* Sartorius Cut to Sector Perform at RBC; PT 260 euros
* SocGen Cut to Reduce at Kepler Cheuvreux
* Steel Dynamics Cut to Equal-Weight at Morgan Stanley; PT $194
* Unicaja Cut to Neutral at BofA (+)
* Vale ADRs Cut to Neutral at Safra; PT $16
* WAG Payment Cut to Equal-Weight at Morgan Stanley; PT 124 pence

>>> Initiation
* Air France-KLM Rated New Neutral at CIC; PT 12 euros (+)
* Autodesk Rated New Buy at Rothschild & Co Redburn; PT $375
* Avanza Rated New Neutral at Goldman; PT 371 kronor (+)
* Dassault Systemes Rated New Neutral at Rothschild & Co Redburn
* DraftKings Rated New Hold at Texas Capital; PT $39
* Empire Metals Ltd Rated New Speculative Buy at Canaccord (+)
* FinecoBank Reinstated Buy at Goldman; PT 25.30 euros (+)
* Flutter Rated New Buy at Texas Capital; PT $294
* Newron Pharma Rated New Buy at Roth Capital Partners
* Nordnet Rated New Buy at Goldman; PT 310 kronor (+)
* Novo ADRs Rated New Outperform at CICC; PT $73.50
* Pharma Mar Rated New Outperform at Grupo Santander; PT 102 euros
* Swissquote Rated New Neutral at Goldman; PT 479 Swiss francs (+)

>>> Call
* Morgan Stanley Sees ‘Notably Improved’ Sentiment on China Stocks

>>> What to look at today - 9th of January 2026 - GLEN/Pharma M&A /Iran/TSMC

Asian equities traded in a narrow range in the run-up to Friday’s US payrolls report and a possible Supreme Court ruling on President Donald Trump’s tariffs. The MSCI Asia Pacific Index opened higher, then fell as much as 0.2%, and then edge up again as markets struggled for direction. Alibaba Group Holding Ltd. rose as much as 4.8% in Hong Kong after China’s plan to approve imports of Nvidia’s H200 chips. Rio Tinto Group shares slumped after the company resumed talks to buy Glencore Plc to create the world’s biggest mining company. Equity-index futures indicated a positive open for European stocks, while contracts for US benchmarks were flat. Treasuries slipped, while a Bloomberg gauge of the dollar was set for its best week since November. During the US session, mortgage-backed securities rallied after Trump said he was directing the purchase of $200 billion of mortgage bonds.  Traders are bracing for two back-to-back risk events on Friday that may sway the mood of the market in the near term, marking one of the biggest tests for global equities since their rebound from April’s tariff-driven slump. The US payrolls for December is particularly important for the clues it will offer on the Federal Reserve’s path for interest rates. Economists surveyed by Bloomberg anticipate 70,000 new positions were added to the US economy in December, slightly higher than the prior month, while the unemployment rate is expected to fall to 4.5%. BNP Paribas Chief Economist Isabelle Mateos y Lago speaks on Bloomberg TV about the growth outlook for equities in 2026, and shares her thoughts on whether optimism towards AI and tech stocks will endure. Jobs data will help illuminate the path ahead for US interest rates. Money markets are pricing in at least two quarter-point cuts from the Fed in 2026.  The Supreme Court is also poised to decide the fate of most of Trump’s tariffs as soon as Friday. Hundreds of companies have already lined up hoping to recoup their share of the billions of dollars in duties paid so far. In other corners of the market, oil extended its gain as investors monitored developments in Venezuela and Iran. Silver and gold edged down. The South Korean won weakened against the dollar as the country announcing introducing 24-hour currency exchange trading in July.
Chinese shares rose after inflation in the nation accelerated at the fastest pace in nearly three years, in an upswing largely driven by higher food costs that are masking deeper deflationary pressure. Mortgage bonds advanced and home-lender stocks in the US rallied after Trump’s move to bring down the cost of housing. There are roughly $9 trillion worth of agency mortgage bonds outstanding. Meanwhile, spreads on global investment-grade corporate bonds are on track to end the week slightly tighter at about 79 basis points on average, according to a Bloomberg index. 
That’s a sign of strong demand for credit, given that more than the $100 billion of the better-rated company notes have been priced this week, in what has been a record start to issuance around the world, data compiled by Bloomberg show. US After Hours GM -2% expects $6 bln EV charge; AXTI -28.5%, PCRX -9.7%, WDFC -9.1% lower on earnings/guidance; KALV +13.8% provides update on EKTERLY launch; Trump wants govt to purchase $200 bln in mortgage bonds.

Nikkei +1.61% Hang Seng +0.23% CSI +0.21% Shanghai +0.71% Shenzen +1.10%

Eur$ 1.1651 CNH 6.9818 CNY 6.9832 JPY 157.35 GBP 1.3429 CHF 0.7998 RUB 80.2789 TRY 43.1518 WTI$ 58.21 +0.76% Gold 4,466 -0.26% BTC 90,900 -0.33% ETH 3,110 -0.12% SOL 139.49 -0.02%

S&P +0.03% Nasdaq +0.03% EuroStoxx +0.34% FTSE +0.24% Dax +0.12% SMI +0.03%

Macro :
- Iran Shuts Down Internet in Crackdown on Escalating Protests,
- Biotech’s M&A hot streak - FT
- Macro Trading’s Big Year Has a Familiar Winner in Louis Bacon
- Sona Adds $6.6 Billion as Investors Look Beyond Big Hedge Funds
- Rokos’ Hedge Fund Joins Macro Peers’ Surge With Gains of 21%
- Qube’s Main Hedge Fund Gained 30%, Torus Made 20% Last Year
- Millennium's corporate strategy head is leaving the $83.5 billion hedge fund
- Luxury Retail Picks Up in China’s Hainan Island, Gold Retailers Shine Brightest - WWD
- NASA to Stage First-Ever Space Medical Evacuation for Astronaut
- Oil Executives to Meet Trump at White House at 2pm Friday: CBS
- Vitol, Trafigura Test US Refiners’ Appetite for Venezuelan Oil
- Market Bubbles Go Way Beyond AI, Says Richard Bernstein Advisors
- European Commission president says Moldova’s progress on EU path is remarkable

Keep an eye on :
- AMZN US : Amazon Won’t Bail Saks Global Out Anytime Soon: Source - WWD
- AAPL US : The Man Who Could Be Apple’s Next C.E.O. - NYT
- AAPL US : Apple CEO 2025 Total Comp. $74.3m vs $74.6m Y/y
- BBNX US : Beta Bionics Shares Fall as Prelim. 4Q Patient Starts Miss
- BEWI NO : KMC Properties Signs Merger Plan With BEWI Invest
- IAG LN : Aer Lingus Halts Ticket Sales on Manchester Long-Haul Flights
- CVNA US : Carvana Robotaxi Effect Makes Morgan Stanley an Even Bigger Bull
- CLASB SS : Clas Ohlson Dec. Sales +5%
- CVC NA : CVC Capital Partners leads race to buy ValueLabs
- 1 HK : CK Hutchison Said to Pick Goldman, UBS for Watson HK-London IPO
- LLY US : Lilly’s Zepbound Plus Arthritis Drug Taltz Eases Joint Pain
- LLY US : Eli Lilly-Backed Aktis Oncology Gets $317.7 Million in US IPO
- ENX FP : Euronext Dec. Total Cash Market Transaction Value Y/y +13%
- FNMA US : Pulte: Trump Told Fannie, Freddie to Buy $200b in Mortgage Bonds
- FRVIA FP : Faurecia: FORVIA and Sinopec Capital partner to accelerate hydrogen growth in China -09th January 2026
- FRO US : Frontline Sells Eight VLCCs, Buys Nine Newbuilds
- GLEN LN : Glencore and Rio Tinto Have Restarted Merger Talks, FT Says
- GM US : GM discloses $7bn hit from EV transition and China restructuring - FT
- GOOGL US : Alphabet Overtakes Apple in Size, Big Tech Mostly Down: TMT Wrap
- GTT FP : GTT Gets Samsung Heavy Order for Tank Design of Two LNG Carriers
- INTC US : Trump Praises Intel After ‘Great Meeting’ with CEO
- JNJ US ; J&J Reaches Pact With US For Tariff Relief, Drug Discounts
- KER FP : Anta Shares Slip After Reported Offer to Buy 29% Stake in Puma
- KMCP NO : KMC Properties Signs Merger Plan With BEWI Invest
- M US : Macy’s Discloses 14 Stores Closing This Year - WWD
- MRK US : Merck in talks to buy cancer drugmaker Revolution Medicines for up to $32bn - FT
- NVDA US : Nvidia-Backed Cloud Provider Lambda in Talks to Raise $350 Million Ahead of IPO - The Information
- ONON US : On Holding Falls as Williams Cuts to Hold on Slower Growth
- PCRX US : Pacira BioSciences Dips, Prelim 4Q Exparel Revenue Misses (1)
- PSKY US : Paramount Skydance Seeks Strategic Partners to Help Reinvent MTV
- 1913 HK : Prada :
- RVMD US : Revolution Medicines Jumps on Report Merck in Talks to Buy
- RIO LN : Glencore, Rio Tinto Confirm in Preliminary Talks
- SCYR SM : Will undertake capital increase of up to €24M via scrip dividend equivalent to €0.05/shr
- SOHO US : Soho House take-private at risk after backer pulls $200mn funding - FT
- Strava IPO : Strava Filed Confidentially for IPO, Hired Goldman Sachs - The Information
- SUNN SW : Sunrise Looks Into Cutting up to 190 Jobs, Including Leadership
- SNBN SW : SNB Profit Weathers Franc Hit With Help From Stocks and Gold
- TMV GY : TeamViewer Prelim FY Revenue Misses Estimates
- TECN SW : Tecan FY Sales Meet Estimates
- TSLA US : *XAI BURNED ABOUT $8 BLN CASH IN FIRST 9 MONTHS OF 2025
- TSLA US : Australia Regulator Raises Concerns About Misuse of Grok
- TGS NO : TGS Says Preliminary M/C Investment ‘Close to’ $120m in 4Q
- TKA GY : Thyssenkrupp Mulls Phased TKSE Sale to Jindal: Rtrs
- TNXT IM : Italy Govt Imposes Tinexta to Separate Defense Assets (Earlier)
- TTAM US : Titan America to Buy Keystone Cement
- 2330 TT : TSMC : TSMC Revenue Beats Estimates In Upbeat Outlook For AI Spending
- VRLA FP : Verallia Says AGCM Investigation to Close, Confirms Compliance
- VIRI FP : Oil-Services Firm Viridien Mulls Selling Sensor Unit to Cut Debt
- YAR NO : Yara Targets $600m Free Cash Flow Expansion With $250m Delivered

>>> Europe : Brokers Upgrades & Downgrades - 9th of January 2026

>>> Up
* Airbnb Raised to Equal-Weight at Wells Fargo; PT $128
* Airbnb Raised to Equal-Weight at Barclays; PT $120
* Altri Raised to Outperform at Grupo Santander; PT 5.49 euros
* Altria Raised to Buy at UBS; PT $63
* Antofagasta Raised to Buy at Goldman; PT 4,000 pence
* Auto Trader Raised to Equal-Weight at Morgan Stanley
* BNP Paribas Raised to Overweight at JPMorgan; PT 102 euros
* Cleveland-Cliffs Raised to Overweight at Morgan Stanley; PT $17
* CrowdStrike Raised to Buy at Berenberg; PT $600
* L'Oreal Raised to Buy at UBS; PT 430 euros
* Marks & Spencer Raised to Buy at Berenberg; PT 415 pence
* Norske Skog Raised to Buy at Pareto Securities; PT 25 kroner
* Scout24 Raised to Overweight at Morgan Stanley; PT 114 euros
* SMG SW Raised to Overweight at Morgan Stanley

>>> Down
* Alcon AG Cut to Hold at Stifel; PT 63.96 Swiss francs
* Aviva Cut to Equal-Weight at Morgan Stanley; PT 670 pence
* BE Semiconductor Cut to Hold at Kepler Cheuvreux
* BMW Cut to Underweight at Barclays; PT 82.50 euros
* Cellnex Cut to Neutral at Goldman; PT 31 euros
* GE Vernova Cut to Neutral at Baird; PT $649
* Hannover Re Cut to Equal-Weight at Morgan Stanley; PT 270 euros
* Herantis Pharma Cut to Reduce at Inderes; PT 2.50 euros
* M&G Cut to Equal-Weight at Morgan Stanley; PT 285 pence
* Metso Cut to Neutral at BofA
* Nucor Cut to Equal-Weight at Morgan Stanley; PT $180
* Porsche Cut to Underweight at Barclays; PT 40 euros
* Rightmove Cut to Underweight at Morgan Stanley; PT 510 pence
* Sandvik Cut to Neutral at BofA
* Sartorius Stedim Cut to Sector Perform at RBC; PT 240 euros
* Sartorius Cut to Sector Perform at RBC; PT 260 euros
* SocGen Cut to Reduce at Kepler Cheuvreux
* Steel Dynamics Cut to Equal-Weight at Morgan Stanley; PT $194
* Vale ADRs Cut to Neutral at Safra; PT $16
* WAG Payment Cut to Equal-Weight at Morgan Stanley; PT 124 pence

>>> Initiation
* Autodesk Rated New Buy at Rothschild & Co Redburn; PT $375
* Dassault Systemes Rated New Neutral at Rothschild & Co Redburn
* DraftKings Rated New Hold at Texas Capital; PT $39
* Flutter Rated New Buy at Texas Capital; PT $294
* Newron Pharma Rated New Buy at Roth Capital Partners
* Novo ADRs Rated New Outperform at CICC; PT $73.50
* Pharma Mar Rated New Outperform at Grupo Santander; PT 102 euros

>>> Call
* Morgan Stanley Sees ‘Notably Improved’ Sentiment on China Stocks

>>> Stoxx 600 Pre-Market Indications

  • Glencore (8GC TH) +10%
    • Rio Tinto, Glencore in Talks to Form World’s Biggest Miner
  • AB Foods (AFO1 TH) +4.1%
    • AB Foods Warns on Profit Hurt by Weaker Primark, Food Sales
  • Shell (R6C0 TH) +2.1%
  • Equinor (DNQ TH) +2.1%
  • Scout24 (G24 TH) +2%
    • Scout24 Raised to Overweight at Morgan Stanley; PT 114 euros
  • Aker BP (ARC TH) +1.7%
  • Repsol (REP TH) +1.7%
  • Puma (PUM TH) +1.3%
  • Rolls-Royce (RRU TH) +1%
  • SocGen (SGE TH) -1%
  • Sartorius (SRT3 TH) -1.6%
    • Sartorius Cut to Sector Perform at RBC; PT 260 euros
  • BMW (BMW TH) -1.9%
  • Cellnex (472 TH) -1.9%
  • Argenx (1AE TH) -2%
  • Porsche (P911 TH) -2.3%
    • Porsche Cut to Underweight at Barclays; PT 40 euros
  • Sandvik (SVKB TH) -2.4%
  • BE Semiconductor (BSI TH) -2.7%
  • Rio Tinto (RIO1 TH) -5.5%
    • Rio Tinto, Glencore in Talks to Form World’s Biggest Miner

>>> TradeGate Pre-Market Indications

DAX:
  • Scout24 (G24 TH) +2.4%
    • Scout24 Raised to Overweight at Morgan Stanley; PT 114 euros
  • Hannover Re (HNR1 TH) -0.8%
    • Hannover Re Cut to Equal-Weight at Morgan Stanley; PT 270 euros
  • BMW (BMW TH) -1.9%
    • BMW Cut to Underweight at Barclays; PT 82.50 euros
MDAX:
  • TeamViewer (TMV TH) +2.4%
    • TeamViewer Prelim FY Revenue Misses Estimates
  • TKMS (TKMS TH) +1.2%
  • RENK Group (R3NK TH) +1.1%
    • RENK Group Investor Raised Voting Rights to 3.02% on Jan. 2
  • Traton (8TRA TH) -1.5%
  • Porsche (P911 TH) -2.4%
    • Porsche Cut to Underweight at Barclays; PT 40 euros
SDAX:
  • SFC Energy (F3C TH) +2.2%
  • Ottobock SE & Co KGaA (OBCK TH) +2.2%
  • PVA TePla (TPE TH) +1.1%

WSJ : Rio Tinto, Glencore in Talks to Form World’s Biggest Miner

Rio Tinto, Glencore in Talks to Form World’s Biggest Miner
A global scramble for copper and other metals is driving the industry’s return to big acquisitions

  • Rio Tinto and Glencore are discussing a deal to form the world’s largest mining company, valued over $200 billion.
  • The potential merger reflects a renewed industry interest in large acquisitions, driven by demand for copper and other metals.
  • Rio Tinto, with a market value of about $145.32 billion, would acquire Glencore, valued at approximately $67.44 billion.

Rio Tinto and Glencore GLEN -2.32%decrease; red down pointing triangle are in talks about a deal that would create the world’s largest mining company with a market value of more than $200 billion, as a scramble for copper and other metals drives an industry return to big acquisitions.

Glencore and Rio Tinto separately confirmed that talks are under way over an all-share deal, revisiting a tie-up that was first discussed around a year ago when the U.S. and other countries began reshaping supply chains for metals and minerals essential to industries such as defense, automaking and semiconductor chips.

The expectation is that Rio Tinto would buy Glencore by way of a court-sanctioned scheme of arrangement, the companies said.

It underscores a shift in thinking among mining executives, who had grown leery about doing big deals after companies overpaid for assets more than a decade ago just as a China-led boom in commodities began to lose steam. Investors at the time pressured companies including Rio Tinto and Glencore to focus on returns, including higher dividends.

“Mining megamergers are back,” Jefferies analysts wrote in a note to clients.

Interest in dealmaking has rekindled as executives and investors worry that their pipeline of new projects isn’t big enough to sustain profits and power share-price growth on its own. The biggest miners had largely anchored their businesses around the production of iron ore and coal, two bulk commodities that were needed by China during its early industrialization.

That focus left many of these miners light on production of copper, which has become a hot commodity as investors bet on rising demand from the roll out of data centers that support the adoption of artificial intelligence and cloud computing.

Doing deals can help miners increase their production faster than building new mines, which typically take years given permitting hurdles and are at risk of cost overruns.

BHP Group, the world’s No. 1 miner by market value, recently made a new bid to acquire Anglo American, a proposal that was rebuffed by its rival. Anglo has agreed to merge with Canada’s Teck Resources in a deal signed off by shareholders of both companies late last year.

Glencore had previously itself bid for Teck and ended up acquiring its steelmaking coal business in 2024.

“BHP wanted Anglo’s copper assets,” Jefferies said. “Anglo wanted and we think is likely to get Teck’s copper assets. And Rio considered a transaction with Glencore, presumably to get leverage to Glencore’s operating copper assets and copper growth projects.”

Glencore owns a stake in the Collahuasi mine in Chile, one of the world’s richest copper deposits, as well as several other copper mines, smelters and refineries globally. Rio Tinto’s copper business includes the Kennecott mine in Utah and a long-delayed project in Arizona that could supply a quarter of U.S. demand of the industrial metal when it starts up.

U.S. copper futures surged to a record this week, reflecting expectations that demand for the metal will rise and supply will be constrained. Data centers contain a lot of copper and need a huge amount of copper-intensive power infrastructure to operate. Electric vehicles and wind farms also use copper in much greater quantities than gasoline-powered cars and coal-fired power plants.

Meanwhile, there have been fewer big discoveries in recent years and resources are deeper underground than ever before. Most of the additional copper resources found in 2025 came from known deposits, according to S&P Global Market Intelligence. It estimates an average 17 years to get a new copper discovery into production.

Rio Tinto’s willingness to discuss a deal with Glencore comes just months after it overhauled its leadership team. In an early memo to employees, Rio Tinto’s new chief executive, Simon Trott, promised “fundamental” changes at a company where he previously ran the iron-ore business. Trott last month outlined plans to cut costs and sell assets.

“We are surprised that Rio has engaged with Glencore on the combination, given the message to investors has been emphasizing ‘simplicity,’” said Prasad Patkar, head of qualitative investments at Sydney-based Platypus Asset Management, which doesn’t have a stake in either company.

Under U.K. takeover rules, Rio Tinto has until Feb. 5 to confirm whether it will make an offer for Glencore or walk away for six months. Its market value is about $145.32 billion and Glencore has a market capitalization of about $67.44 billion, according to FactSet.

Glencore’s American depositary receipts rose by 8.8% in New York. Rio Tinto shares were roughly 6% lower by midafternoon in Sydney. Rio Tinto is dual listed in Australia and the U.K.

Jefferies said one possibility is that Rio Tinto and Glencore merge their iron-ore and coal businesses as an Australian-listed company, and then separate their base-metals assets under a different entity. But that kind of deal could be difficult to structure and come with a big tax burden, they said.

Another possibility is that Glencore offloads its coal business and then sells itself to Rio Tinto.

Rio Tinto, which exited the coal industry in 2018, has sought to diversify away from iron ore, which accounted for almost 80% of its earnings as recently as 2024. A combined company without coal would make most of its money from copper, followed by iron ore and aluminum, Jefferies said.

“We would not expect Glencore to get taken out in a nil-premium merger,” Jefferies said.

TechCrunch : CES 2026: Everything revealed, from Nvidia’s debuts to AMD’s new ch

CES 2026: Everything revealed, from Nvidia’s debuts to AMD’s new chips to Razer’s AI oddities

CES 2026 is in full swing in Las Vegas, with the show floor open to the public after a packed couple of days occupied by press conferences from the likes of Nvidia, Sony, and AMD and previews from Sunday’s Unveiled event.
As has been the case for the past two years at CES, AI is at the forefront of many companies’ messaging, though the hardware upgrades and oddities that have long defined the annual event still have their place on the show floor and in adjacent announcements. We’ll be collecting the biggest reveals and surprises here, though you can still catch the spur-of-the-moment reactions and thoughts from our team on the ground via our live blog right here.

Let’s dive right in, starting with some of Monday’s biggest players.

Nvidia reveals AI model for autonomous vehicles, showcases Rubin architecture
Nvidia CEO Jensen Huang delivered an expectedly lengthy presentation at CES, taking a victory lap for the company’s AI-driven successes, setting the stage for 2026, and yes, hanging out with some robots.
The Rubin computing architecture, which has been developed to meet the increasing computation demands that AI adoption creates, is set to begin replacing Blackwell architecture in the second half of this year. It comes with speed and storage upgrades, but our senior AI editor Russell Brandom goes into the nitty-gritty of what distinguishes Rubin.
And Nvidia continued its push to bring the AI revolution into the physical world, showcasing its Alpamayo family of open source AI models and tools that will be used by autonomous vehicles this year. That approach, as senior reporter Rebecca Bellan notes, mirrors the company’s broader efforts to make its infrastructure the Android for generalist robots.

AMD’s keynote highlights new processors and partnerships
AMD chair and CEO Lisa Su delivered the first keynote of CES, with a presentation that featured partners, including OpenAI president Greg Brockman, AI legend Fei-Fei Li, Luma AI CEO Amit Jain, and more.
Beyond the partner showcases, senior reporter Rebecca Szkutak detailed AMD’s approach toward expanding the reach of AI through personal computers using its Ryzen AI 400 Series processors.

The standout oddities of CES
Let’s face it, by this point in the show the major announcements have been made, products have been showcased, and it’s time to eye some of the most brow-raising reveals from CES. We started our list of what stood out to us as odd and noteworthy, but we’re open to more suggestions!

Highlights from CES breakout sessions
CES isn’t all hardware showcases and show floor attractions — there are plenty of additional industry panels and speakers drawing eyeballs. We kept tabs on a few notable highlights, ranging from Palmer Luckey pushing retro aesthetics, to why the “learn once, work forever” era may be over, to previews of the new Silicon Valley-based series “The Audacity,” to the expansion of Roku’s $3 streaming service, to All-In host Jason Calacanis putting a $25,000 bounty on an authentic Theranos device.

Ford’s AI assistant debuts
Ford is launching its assistant in the company’s app before a targeted 2027 release in its vehicles, with hosting managed by Google Cloud and the assistant itself built using off-the-shelf LLMs. As we noted in our coverage of the news, however, few details were offered around what drivers should expect from their experience with the assistant.

Caterpillar, Nvidia partner on automated construction equipment
As part of the ever-present push for AI’s impact on the physical world, Caterpillar and Nvidia announced a pilot program, “Cat AI Assistant,” which was demonstrated at CES Wednesday. This system, coming to one of Caterpillar’s excavator vehicles, is happening alongside another project to use Nvidia’s Omniverse simulation resources to help with construction project planning and execution.

Hands-on with Clicks Communicator
Image Credits:TechCrunch
One of the buzziest reveals of the show is the debut phone from Clicks Technology, the $499 Communicator, which brings back BlackBerry vibes with its physical keyboard, plus a separate $79 slide-out physical keyboard that can be used with other devices.

Check out our full rundown from the show floor here, but the Communicator makes a good first impression, per Consumer Editor Sarah Perez:
“In our hands-on test, the phone felt good to hold — not too heavy or light, and was easy to grip. Gadway told me the company settled on the device’s final form after dozens of 3D-printed shapes. The winning design for the phone features a contoured back that makes it easy to pick up and hold.
“The device’s screen is also somewhat elevated off the body, and its chin is curved up to create a recess that protects the keys when you place it face down.”

Check out the Skylight Calendar 2
Image Credits:Sarah Perez
This family planning tool caught our eyes on the show floor, not just for its calendar and planning capabilities, but for its AI capabilities that are able to sync calendars from different sources, create new to-dos based off of messages or photos, appointment reminders, and more. Check out our full impressions here.

Boston Dynamics and Google partner on Atlas robots
Hyundai’s press conference focused on its robotics partnerships with Boston Dynamics, but the companies revealed that they’re working with Google’s AI research lab rather than competitors to train and operate existing Atlas robots, as well as a new iteration of the humanoid robot that was shown onstage. Transportation editor Kirsten Korosec has the full rundown.

Amazon expands Alexa, Ring’s footprints even further
Amazon’s AI-centric update with Alexa+ is getting the kind of push you’d expect at CES, with the company launching Alexa.com for Early Access customers looking to use the chatbot via their browsers, along with a similar, revamped bot-focused app. Consumer editor Sarah Perez has the details, along with news on Amazon’s revamp to Fire TV and new Artline TVs, which have their own Alexa+ push.
On the Ring front, consumer reporter Ivan Mehta runs through the many announcements, from fire alerts to an app store for third-party camera integration, and more.

Razer joins the AI deluge with Project AVA and Motoko
In the past, Razer has been all about ridiculous hardware at CES, from three-screen laptops to haptic gaming cushions to a mask that landed the company a federal fine. This year, its two attention-grabbing announcements were for Project Motoko, which aims to function similarly to smart glasses, but without the glasses.

Then there’s Project AVA, which puts the avatar of an AI companion on your desk. We’ll let you watch the concept video for yourself.

Lego Smart Bricks mark the company’s first CES appearance
Lego joined CES for the first time to hold a behind-closed-doors showcase of its Smart Play System, which includes bricks, tiles, and Minifigures that can all interact with each other and play sounds, with both the debut sets having a Star Wars theme. Senior writer Amanda Silberling has all the details here.

TechCrunch : Data security startup Cyera hits $9B valuation six months after bei

Data security startup Cyera hits $9B valuation six months after being valued at $6B

Data security startup Cyera continues on a growth tear. On Thursday, it announced a $400 million Series F funding round at a $9 billion valuation. The New York-based outfit has now raised over $1.7 billion. This funding comes just six months after the previous $540 million round at a $6 billion valuation.

The new round was led by funds managed by Blackstone with participation from existing investors including Accel, Coatue, Lightspeed, Redpoint, Sapphire, Sequoia, and others.

Cyera offers what it calls data security posture management, a service that helps companies map out where all their sensitive data lives across cloud systems and databases, track how employees and applications use it, and identify security vulnerabilities. The rise of AI — which has increased both the volume of data that companies handle and concerns about data leaks — has helped Cyera sign up one-fifth of the Fortune 500 companies as customers and more than triple revenue in its last year, the company says, causing investors to eagerly pile in.