>>> US Gapping up

Gapping up
In reaction to earnings/guidance
:

  • SCS +5.2%, ACN +4.4%, GMS +2.2%

Other news:

  • ARAV +23.1% (announces "positive" initial results from the Phase 1b portion of its Phase 1b/2 study in patients dosed with 15mg/kg of AVB-500 in combination with cabozantinib who have clear cell renal cell carcinoma)
  • DHX +19% (announces additional $12 mln authorization under share buyback program)
  • RCUS +18.6% (Phase 2 ARC-7 study with domvanalimab-based combinations showed encouraging clinical activity)
  • KUKE +8.8% (Kuke Music Holding's KUKEY Lessons have been included in China's pre-school music education curriculum and deployed in more than 4,000 kindergartens across China)
  • LLY +7.3% (donanemab receives FDA's Breakthrough Therapy designation for treatment of Alzheimer's disease)
  • ARAY +6.8% (Family pet's lung cancer is treated with targeted radiotherapy using the Accuray Radixact System with Synchrony Technology; Mac, a Fox Terrier Mix, is doing well following radiotherapy treatment)
  • AGTC +5.8% (reports 12-month data from its ongoing phase 1/2 achromatopsia clinical trials showing biologic activity in patients with mutations in the ACHM B3 Gene)
  • FSP +5.3% (authorizes the repurchase of up to $50 mln)
  • BOCH +4.6% (Bank of Commerce to merge into Columbia Banking System (COLB) in all-stock transaction)
  • KPTI +4.5% (expands royalty agreement with HealthCare Royalty Management for up to $100 mln)
  • FSLR +4.2% (US to block some solar goods made in Xinjiang region, according to Bloomberg)
  • KOR +3.7% (received additional drill hole results from the Mother Lode mineral resource expansion program)
  • KZIA +3.3% (granted patents by the respective agencies of the United States and India in respect of the manufacturing process for paxalisib)
  • IPI +3.2% (announces increase to potash and Trio pricing)
  • ZEAL +2.9% (announced that ZEGALOGUE (dasiglucagon) injection 0.6mg/0.6mL is now commercially available in the U.S. in both an auto-injector and prefilled syringe) LODE +2.2% (to purchase an additional 5% of its 45%-owned technology development partner Quantum Generative Materials in exchange for $50 million)
  • VKTX +2% (announces the initiation of a Phase 1b clinical trial of VK0214, a novel small molecule agonist of the thyroid hormone receptor beta, in patients with X-linked adrenoleukodystrophy)
  • PACB +1.3% (announces collaboration for whole genome sequencing)
  • ALNY +1.3% (announces FDA acceptance of new drug application for investigational vutrisiran for the treatment of the polyneuropathy of hereditary ATTR amyloidosis)
  • MPW +1.1% (MPW to acquire five hospitals from THC for $900 mln)
  • VRAY +1% (GenesisCare expanded its partnership with ViewRay)

Analyst comments:

  • MGA +3% (upgraded to Buy from Neutral at Goldman)
  • LEA +2.6% (upgraded to Buy from Neutral at Goldman)
  • CS +2.5% (upgraded to Buy from Hold at Berenberg)
  • MGM +2.5% (upgraded to Buy from Hold at Deutsche Bank)
  • APTV +1.8% (upgraded to Buy from Neutral at Guggenheim)
  • STX +1.5% (upgraded to Outperform from Market Perform at Northland Capital)