>>> US Gapping down

Gapping down
In reaction to disappointing earnings/guidance
: PDVW -6.6%, BIDU -4.3%, PFIE -1.8%, MPAA -1%

Select Large pharma names showing weakness: NVO -4.2%, SNY -2.9%, AZN -2.1%, GSK -2%, NVS -1.1%

Select metals/mining stocks trading lower: BBL -2.6%, BHP -2.4%, RIO -1.9%, MT -1.8%

Select oil/gas related names showing early weakness: HCLP -3.8%, SDRL -2.4%, EMES -2.2%, BP -2%, SSL -1.9%, PBR-1.8%, RDS.A -1.8%

Other news: INFI -66% (announces 21% workforce cut, pause of AbbVie (ABBV) Phase 1b/2 study evaluating duvelisib in combination with venetoclax, and DYNAMO Phase 2 met primary end point), MESO -39.9% (provides update on global heart failure program; regains rights to cardiovascular field for cell therapy platform), RVNC -23.7% (reports results from its REALISE 1 Phase 3 trial of RT001; did not achieve its co-primary and other endpoints), KMPH -20.5% ( issued a CRL by the FDA regarding its Apadaz NDA ), IMGN -11.1% ( to offer and sell to the initial purchasers $100 million aggregate principal amount of convertible senior notes due 2021), WGP -9.3% (Western Gas Resources, a subsidiary of Anadarko Petroleum (APC), has commenced 12.5 mln unit offering of common units representing lp interests in the Partnership), INNL -5.9% (Innocoll to conduct an underwritten public offering of up to $65 mln of its ordinary shares by itself and selling shareholders), NERV -5.1% (to offer and sell common stock in an underwritten public offering), ZBH -2.5% (prices ~11.1 mln common stock offering by certain of its stockholders, consisting of affiliates of KKR, Goldman Sachs and TPG at $115.85/share)

Analyst comments: NAV -3.7% (downgraded to Sell from Hold at Stifel), WNC -3% (downgraded to Sell from Hold at Stifel),CDNS -0.9% (downgraded to Hold from Buy at Needham)